In 1970 he moved to the University of North Carolina at Chapel Hill where he followed T. Robert S. Broughton as George L. Paddison Professor of Latin.
[1] While at Stanford Otis was one of the founders of the Intercollegiate Center for Classical Studies in Rome, Italy, in 1965.
Otis was known for some of the most concise and penetrating critical essays written on classical literature.
His first book, published at the age of 55, was Virgil: A Study in Civilized Poetry (1963),[2] which was immediately recognized as a classic.
[3] He also wrote Ovid as an Epic Poet (1966)[4] and the posthumous Cosmos and Tragedy: An Essay on the Meaning of Aeschylus (1981), edited with notes and a preface by E. Christian Kopff),[5] which was part of a long manuscript left unfinished at his death, entitled "The Transcendence of Tragedy".