He played college football for the Louisville Cardinals and was selected by the Jets in the second round of the 1991 NFL draft.
When it became clear that West Virginia would go with Harris and an option offense, Nagle transferred to Louisville and played for Howard Schnellenberger.
He threw for a total of 2,361 yards as a Jet with 199 completions on 403 attempts with seven touchdowns and 17 interceptions over that three-year span with a win-loss record of 3–10.
In 1994, he started in one game for the Indianapolis Colts throwing eight completions on 21 attempts and 69 yards with no touchdowns and one interception in his lone win of the season.
[3] In 1999, Nagle joined the Orlando Predators of the Arena Football League and made 146 completions on 275 attempts for 1,991 yards, 39 touchdowns, and nine interceptions.