Dreisbach played professional football for the Oakland Raiders from 1999 to 2000, but he was injured prior to the start of the regular season each year.
Dreisbach led Michigan to a 4–0 record in the first four games of the 1995 season, but he suffered a serious injury to his right thumb and wrist after a collision with a teammate during practice.
[6] In 1996, Dreisbach rebounded from his injury to beat out Brian Griese and sophomore Tom Brady as the Wolverines' starting quarterback.
[11] In 12 games as a starter during the 1995 and 1996 seasons, Dreisbach led the Wolverines to a 12–4 record and completed 205 of 375 passes for 2,875 yards, 15 touchdowns and 12 interceptions.
[11] Despite not starting a game during his junior and senior seasons, Dreisbach was signed by the Oakland Raiders as an undrafted free agent.
[14] Despite the injury, the Raiders kept Dreisbach on the active roster during the 1999 NFL season so he could still attend all team meetings and work with the coaching staff during his recovery.
He entered the Raiders' 2000 training camp competing with Rodney Peete for the #3 quarterback behind Rich Gannon and Bobby Hoying.
[18] Dreisbach next played in the Arena Football League (AFL) for the Los Angeles Avengers in 2003, the Dallas Desperados in 2004, the Austin Wranglers in 2005, the Georgia Force in 2006 and the Columbus Destroyers in 2007.
[2] In 2014, he joined his grandfather and uncle in the Indiana Football Hall of Fame; he was inducted in recognition of his high school, college and professional careers.