[1] As a senior, Brown led his team to the New England Preparatory School Athletic Council Class AA title and was named tournament most valuable player.

[6] As a sophomore with the Miami Hurricanes, Brown averaged 11.4 points, 7.1 rebounds and four assists per game and shot 27 percent from three-point range.

[10][11] Brown made his NBA debut on October 17, 2018, against the Brooklyn Nets, scoring no points with two rebounds and an assist in 19 minutes of action.

[19] The Nets had chosen not to match the Nuggets' taxpayer mid-level exception offer for Brown and acquired Royce O'Neale as a replacement instead.

On October 25, 2023, Brown impressed in his Pacers debut, scoring a team-high 24 points with a career-high 6-of-8 three-point shooting performance, along with three rebounds and a steal in a 143–120 win over the Washington Wizards.

[25] On January 17, 2024, the Pacers traded Brown, along with Jordan Nwora, Kira Lewis Jr. and three first-round draft picks to the Toronto Raptors in exchange for Pascal Siakam.

[26] On February 6, 2025, the Raptors traded Brown, Kelly Olynyk and multiple draft picks to the New Orleans Pelicans in exchange for Brandon Ingram.