The club competed in the Victorian Amateur Football Association (VAFA) almost continuously from 1926, winning a total of six senior premierships.

[7] At one point in 1939, the VAFA instructed the club to find another home ground to play at as it was in a "shocking condition".

[8][9] They were defeated by Elsternwick later that year in the B Section grand final where a melee also took place, resulting in Brunswick being warned by the VAFA about "drastic action" if a similar incident happened again.

[10][11] Brunswick won its second premiership in 1955, defeating East Malvern by 32 points in the C Section grand final.

[2][12] At the end of the 1994 season, Brunswick left the VAFA and joined the Footscray District Football League (FDFL).