Prior to joining TSN, Mudryk was a sports anchor and reporter at CTV Edmonton between 2001 and 2005.

Mudryk is a regular in the broadcast booth for TSN's Season of Champions curling, covering the Scotties Tournament of Hearts and Tim Hortons Brier, as well as hosting the Pinty's All-Star Curling Skins Game and Continental Cup.

[4][5] Prior to the start of the 2018/19 National Hockey League season, Mudryk was named play-by-play announcer for the network's Montreal Canadiens regional broadcasts.

His tournament, the annual Bryan Mudryk Golf Classic, has raised over 1.8 million dollars for the Cross Cancer Institute in Edmonton.

[2] The foundation has also launched a special scholarship for post-secondary students undergoing treatment for cancer.