The school was named for Bryan Station, an 18th-century pioneer settlement.

The school's sports teams are called the Defenders, and the school mascot is the "Mean Man"; the school says "His persona reflects the heritage of the pioneers at the siege of Bryan Station Fort between the British and Indians in 1782.

"[1] The Defenders support 15 different sports teams including football, basketball, soccer, baseball, wrestling, softball, volleyball, tennis, lacrosse, swimming and track and field.

[5] The Defenders' football team won the 1971 2A title.

[6] The Defenders' boys track team took home titles in 1971, 1975, and 1979–83.