Bryantsburg is an unincorporated community in Monroe Township, Jefferson County, Indiana.

Its operation had probably ended by April 30, 1867 when the church trustees sold the lot and meeting house.

It was located about a mile north of Bryantsburg on the west side of the Michigan Road.

The town was described in an 1889 history: "Bryantsburg: Monroe township, was laid off by Jacob Bryant, March 5th, 1834.

The Indiana Gazetteer and Business Directory of 1890 described Bryantsburg thus: "An incorporated village located in Monroe township, Jefferson county, 10 miles north of Madison, the county seat, usual banking, and shipping point.