Previously he served as the head coach of the Vanderbilt Commodores and in the same capacity at his alma mater, Valparaiso, having succeeded his father, Homer Drew.

As a player, Bryce Drew was known for his buzzer-beating shot in the first round of Valparaiso's run in the 1998 NCAA tournament.

As he progressed through high school though, Drew developed a rapid heartbeat,[1] which required three surgeries to repair.

[3] Though recruited by dozens of schools,[4] Drew eventually decided to attend Valparaiso University, then a member of the Mid-Continent Conference, for men's basketball.

In his four years playing, Drew collected dozens of honors and records, including being ranked in the top 15 nationally in 3-point field goal and free throw percentage and leading the team to three consecutive conference regular season and tournament championships.

Valparaiso was down 69–67 with 4.1 seconds remaining in the game and Mississippi's Ansu Sesay at the free throw line.

Drew made a 23-foot 3-point shot, giving him his 22nd point of the night, and clinching the Crusaders' 70–69 upset and advancing them in the tournament.

"[7] In the summer of 2005, Drew was selected as the new assistant coach of the Valparaiso University men's basketball team.

"[10] The Commodores qualified for the NCAA tournament in his first year coaching at Vanderbilt in 2016–2017, narrowly losing to Northwestern in the first round.

[15] The best showing of the year for Vanderbilt was narrowly losing in overtime to AP #1 Tennessee Volunteers basketball 88–83.

[17] On March 17, 2020, Drew was hired as the head coach of Grand Canyon, replacing Dan Majerle.

[18] On March 6, 2021, Drew coached Grand Canyon to its first WAC regular-season championship in school history.

He netted his first career win in the NCAA tournament when the 12th-seeded Lopes upset 5th-seeded Saint Mary's[23] before losing to eventual Final Four qualifier Alabama after leading with under six minutes to play.

To be able to go into a young man's house and sit down with him to map out his future and then have them achieve those goals and dreams four years later is a great feeling.