Bubble Boy is a 2001 American black comedy film directed by Blair Hayes, starring Jake Gyllenhaal in the title role.

Born without an immune system, Jimmy Livingston lives in a sterilized dome in his bedroom in his home in California, earning him the nickname "Bubble Boy" by his neighbors.

Encountering his parents on the road, Jimmy is struck by their vehicle and bounced aboard a train belonging to Dr. Phreak, who shows "freaks" to the public for money.

Jimmy is picked up by Pushpop, an Indian ice cream truck driver, but has to continue on foot when they hit a cow on the road.

Winning $500 in a mud wrestling competition, Jimmy pays taxi driver Pappy for a ride but is cornered by the cult members.

Discouraged, Jimmy intends to return home with his parents, but encouragement and an opening provided by his father Morton allows him to escape on a plane piloted by Pappy's twin brother Pippy.

[8] The film was the center of a brief controversy for downplaying the effects of severe combined immunodeficiency (SCID) for the purposes of comedy, which affected the life of David Vetter, another child who lived in a bubble and died at age twelve.