[2] As he had three older brothers, he had to earn a living from a profession, so Buchanan studied medicine at the University of Edinburgh, graduating MD in 1783.
Hope was among the first to teach the Linnean system of botanical nomenclature, although he knew of several others having been trained under Antoine Laurent de Jussieu.
From 1807 to 1814, under the instructions of the government of Bengal, he made a comprehensive survey of the areas within the jurisdiction of the British East India Company.
He was asked to report on topography, history, antiquities, the condition of the inhabitants, religion, natural productions (particularly fisheries, forests, mines, and quarries), agriculture (covering vegetables, implements, manure, floods, domestic animals, fences, farms, and landed property, fine and common arts, and commerce (exports and imports, weights and measures, and conveyance of goods).
[5] Buchanan's conclusions are reported in a series of treatises that are retained in major United Kingdom libraries; many have been reissued in modern editions.
He succeeded William Roxburgh to become the superintendent of the Calcutta botanical garden in 1814, but had to return to Britain in 1815 due to his ill health.
[citation needed] From 1814 until 1829 he was the official Keeper of the Royal Botanic Garden, Edinburgh succeeding William Roxburgh.