Budrio is the birthplace of Giuseppe Barilli, better known under his pseudonym of Quirico Filopanti, an Italian mathematician and politician.

The area around Burdio was a Roman colony, whose territory was divided between veteran legionaries.

In the 14th century Cardinal Gil de Albornoz rebuilt it as a castle, of which the two large towers (1376) can still be seen, while of the walls only a small section remains.

The most notable attraction are the Bentivoglio castle (16th century) and the Villa Ranuzzi Cospi at Bagnarola.

The town also houses an art gallery- Pinacoteca Domenico Inzaghi- and the churches of San Domenico del Rosario, San Lorenzo, and Santi Gervasio e Protasio.