Powered by the overhead valve (OHV) Buick straight-6 engine, it was the junior model to the Buick Master Six, and shared the GM A platform with Oldsmobile, Oakland and Chevrolet.

The Standard Six was the most popular Buick sold while being more upscale to the Oldsmobile Six.

Coachwork continued to be offered by Fisher Body, which was the primary supplier of all GM products at this time, and its Duco automotive lacquer paint, introduced by DuPont was the first quick drying multi-color line of nitrocellulose lacquers made especially for the automotive industry.

[1] The Series 20 was manufactured at what would later become known as the Buick City factory on Hamilton Ave. in Flint, Michigan.

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