It was first set up to train elementary school teachers for the provinces of Northern Mindanao and the neighboring regions.

It was reactivated on September 1, 1945, but since its facilities were completely damaged, classes were held in army tents at the provincial capitol grounds and in private homes.

The gradual elimination of the secondary education ended in 1956 with the full implementation of the two-year collegiate course.

In the same year, the two-year special curriculum was phased out and the school gained the status of a degree-granting institution.

In 1960, the graduate department was created, offering a master's degree in education to encourage teachers to take advanced studies.

Ten years later, external graduate studies centers were organized in a number of provinces and cities outside of Bukidnon in cooperation with the school divisions of the Department of Education to extend the services of the college to working teachers wanted to enroll in courses leading to Master of Arts in education.

[8] On July 23, 2024, the Advancing Research and Technological Innovation Fabrication Laboratory was established at Bukidnon State University.

Founded in 1974, the SLS three-story new edifice features security equipment, a gymnasium and a solar power system.

SLS Department Head Desiree A. Barroso announced its capacity for 387 junior and senior high school students.

2751, Series of 2024 duly authorized BukSU to retain its senior high school program in the SLS.