The University of Science and Technology of Southern Philippines (USTP; Filipino: Pamantasan ng Agham at Teknolohiya ng Dakong Timog ng Pilipinas[1]) is a state university system in the Philippines established on August 16, 2016, by virtue of Republic Act 10919 through the amalgamation of the Mindanao University of Science and Technology (MUST) in Cagayan de Oro and the Misamis Oriental State College of Agriculture and Technology (MOSCAT) in Claveria, Misamis Oriental.

It was named as the Misamis Oriental Trade School (MOTS) which catered to the elementary level only but eventually in 1936, it opened a secondary four-year program.

Later in 1970, the school was authorized by virtue of RA 3959 to offer Bachelor of Science in Industrial Education and the Evening Opportunity Programs.

In 1991, it was renamed Mindanao Polytechnic State College (MPSC) and it also gained a new function – provide extension services.

On October 3, 2008, the historic Senate Public Hearing happened at the university gymnasium with Sen. Miguel Zubiri as the presiding officer.

The occasion was graced by senators, congressmen, local officials, civic organizations, GOs, private sectors, higher education institutions and stakeholders.