In December 2011, Lee announced that Bullet Brain is slated to begin filming in May 2012, but remained tight-lipped on the other details of the production.

[1] However, due to the studio's decrease in staff capacity, Lee lost many of his creative directors and scriptwriters, which will affect the pace of production.

[1] He further added that the cast seen in Bullet Brain's presentation trailer are not confirmed to star, with the exception of Wayne Lai.

The serial's main character, a brilliant but cold-blooded detective from the Hong Kong Police Force (HKPF).

Born Ko Tai-hei, Columbo was originally an innocent and simple-minded farmer from the outskirts of mainland China.

After recovering from a bullet to the head, Tai-hei's temperament suffers a dramatic change — his IQ rises from 100 to 283, and his emotional capacity is almost entirely destroyed.

She immediately regrets her initial decision in leaving him twenty years ago and attempts to win his heart back.

Siu reportedly rejected a high-paying production in order to accommodate his schedule to film Bullet Brain.

Cunning and thirsty for power, Scott's goals are clear and he plans to overthrow Louis as the Head of Security.

Louis was a friend of Tai-hei's father Ngau, whom he met in the concentration camps during the Japanese occupation of Hong Kong.

After Ngau's death, Louis recruits his son, the childlike Tai-hei, into the Hong Kong Police Force as a gesture of gratitude.

The premiere episode received an average rating of 28 points, at approximately 1.79 million live viewers in Hong Kong.

"[11] As of May 2013, Bullet Brain is TVB's lowest-rated serial drama of the year, raking in only an average of 1.55 million viewers.