The Burkinese delegation to London consisted of two athletes, Lassane Gasbeogo and Kadidia Nikiema, who competed in wheelchair cycling at the Brands Hatch race circuit in Kent.

Neither athlete won any medals in their respective events, with the best finish of Burkina Faso at these Paralympics coming from Nikiema in the women's road trial H3 race with a sixth-place result.

[5] The five-person team, comprising the athletes, a trainer, a physiotherapist,[6] and chef de mission Florentine Ouedraogo, arrived at Gatwick Airport from Burkina Faso on 6 August.

[7][8] This caused meet-and-greet volunteer and student Liam Conlon to take the male delegates to his home in Abridge, Essex; the women resided with local nuns in Brentwood after they were unable to stay in the accommodation arranged through Kent County Council.

[3][9] Their handcycle was subsequently deemed to be in non-compliance with Paralympic specifications and the team contacted suppliers from the United Kingdom and overseas since they lacked time to do fundraising.

[8] They developed a more permanent relationship with Brentwood School, with its pupils and teachers organising a non-uniform day,[3] dressing up in the colours of the flag of Burkina Faso as a mark of respect and to raise capital for the team.

[8][9] Conlon spoke of the reception the team received in Brentwood, "I had no idea how much of a community there was in the UK before they arrived, there were so many people involved in helping them, and the athletes loved everyone they met.

[13] Both of Burkina Faso's athletes competed in road cycling events at the Brands Hatch race track in Kent from 5 to 8 September.

[14] He commented on his prospects in the Games, "The problem in Beijing is the equipment we had just wasn't good enough, but the bike we have now is much better We are just a small team – there are only two of us competing – but we are so proud to be representing our country.