Great Britain competed at the 2012 Summer Paralympics in London, United Kingdom, from 29 August to 9 September 2012 as the host nation.

Despite the team being made up of athletes from the whole United Kingdom they compete under the name of Great Britain, a name first assigned by the International Olympic Committee (IOC) for the 1908 Summer Olympics along with the IOC country code GBR, and later used by the International Paralympic Committee for the Paralympic Games.

[14] On 10 July 2012 the British Paralympic Association named a 49-member squad to compete for Great Britain in athletics, although Andy Kaar was later forced to withdraw due to injury.

[24] In the men's B time trial, the tandem of Anthony Kappes and pilot Craig MacLean twice had a mechanical problem with their chain and were not allowed a second restart.

[25] Both pairings met in an all-British final in the men's B sprint event, where Kappes and MacLean won the gold medal after breaking the world record time during the qualification round.

[28] In the women's H1-3 road race, Karen Darke and Rachel Morris finished together in the same time holding hands.

[38] Captain David Clarke scored in his final international match as Britain defeated Turkey 2–0 to win the classification playoff for seventh place.

[45] As hosts, Great Britain were entitled to enter a team in the men's and women's goalball tournaments,[46] and competed for the first time since the 2000 Games.

[50] No other British judoka reached the semifinals, but Ben Quilter advanced through the repechage contest to win a bronze medal in the –60 kg category after defeating Japan's Takaaki Hirai by ippon.

[51] Six powerlifters were named in the GB team,[52] although Paul Efayena was barred from participating due to a previous criminal conviction.

[55] The mixed adaptive double crew of Captain Nick Beighton and Sam Scowen qualified for London 2012 at the World Rowing Championships.

Nick Beighton and Sam Scowen came fourth in the mixed double sculls, missing out on bronze in a photo finish.

[59] Tom Aggar finished in fourth place in the final of the men's single sculls, his first defeat in five years of international racing.

A squad of twelve competitors were selected to take part in the shooting events including 2008 gold medal winner Matt Skelhon and Di Coates, who first competed at the 1984 Games, making her eighth Paralympic appearance.

James Bevis won a bronze medal in the 10 m air rifle prone SH2 event, losing a shootoff to Raphaël Voltz of France 10.4–10.5 after both scored a total of 705.9.

[67] The British Paralympic Association announced that the men's and women's teams would take up their home quota places in September 2011 and March 2012 respectively.

[68] The women's team, including 7 July 2005 London bombings survivor Martine Wright, finished eighth without winning a set.

[72] British Swimming selected 44 swimmers[3] for the Paralympic Games based on qualifying times set at trial events in London and Sheffield in March and April 2012 respectively.

[78] S7 swimmers Josef Craig and Jonathan Fox both posted new world record times on the way to gold in the 400 m freestyle and 100 m backstroke respectively.

[81] Gold medals were also won by S8 swimmers Heather Frederiksen in the women's 100 m backstroke[82] and Oliver Hynd, who set a new European record in the men's 200 m individual medley SM8.

[84] Qualifiers for the latter rounds (Q) of all events were decided on a time only basis, therefore positions shown are overall results versus competitors in all heats.

Qualifiers for the latter rounds (Q) of all events were decided on a time only basis, therefore positions shown are overall results versus competitors in all heats.

Will Bayley won a silver medal in the class 7 men's singles, losing to Jochen Wollmert of Germany in the final.

[89] Competing athletes are given an eight-level-score specific to wheelchair basketball, ranging from 0.5 to 4.5 with lower scores representing a higher degree of disability.

[90] The men's team were defeated by Canada in the semi-final and went on to finish fourth after losing the bronze medal final to the US.

The squad included 14-year-old Gabi Down as well as 1992 bronze medallist David Heaton who returned to the sport having retired after the 2004 Paralympics.

Tom Hall-Butcher advanced from the opening qualification pools but lost to Cheong Meng Chai of Hong Kong in the last 16 round.

Peter Norfolk and Andy Lapthorne won a silver medal in the quad doubles, losing the final against defending champions Nicholas Taylor and David Wagner of the US in three sets.