Busalla is a comune (municipality) in the Metropolitan City of Genoa in the Italian region Liguria, located about 27 kilometres (17 mi) north of Genoa.

Its territory is crossed by the upper valley of the Scrivia river.

Later it is known to have been held by the Spinola family, who here built a castle.

This was sacked several times in the following century, in the course of the Wars of Guelphs and Ghibellines.

In the 16th century the structure, again in ruins, was used as foundation of a new palace for the Spinola.