It begins at the northern end of Power Road in Mesa and extends northeasterly through the Tonto National Forest to the Beeline Highway.

The highway was named for local resident Harvey Grandville Bush in the 1930s.

Near the Salt River, the roadway turns to the northeast into Tonto National Forest.

The highway runs over the Arizona Canal and past the Granite Reef Dam.

From there, the road continues northerly past the Stewart Mountain Dam and Saguaro Lake to connect with State Route 87 (Beeline Highway).