[2] The drugstore was noted as a local attraction in Corydon, due in part to its unique name.

Additionally, the store offered curb-side service to deliver prescriptions to customers' vehicles.

[2] A 2019 article published by WCPO stated that the store was known for its "priority on family friendly service" and was considered an integral part of the community.

[2][4] In 2010, YouTube personalities Rhett & Link gave the store further attention when, as part of a project to film commercials for small local businesses, they recorded one for Butt Drugs.

Employees of Butt Drugs noted that sales of T-shirts for the store increased greatly after Rhett & Link's commercial became a viral video.