In 1958 Deportes La Serena for the first time participated in first division and finished third, tying in Colo-Colo score and one point behind champion that year Santiago Wanderers.

During this season, club striker Carlos Verdejo was the scorer of the championship with 23 points, next to the player, Green Cross, Gustavo Albella.

The 1960s began with the club again reached the final of the Copa Chile, where defeated by 4–1 to Santiago Wanderers and were crowned champions of the tournament.

For the play-offs (qualified in 2002), only ranked in the Torneo Clausura 2005 where he progressed to the semi-finals Colo-Colo, after a draw in matches Round-trip 1–1 and 3–3, by definition a criminal, which fell to Universidad Católica (3–3 and 1–0).

The stadium was opened on 26 August 1952 and at first it was a dirt field, filling in until November 1955, coinciding with the arrival of professionalism Deportes La Serena.

Current squad of Deportes La Serena as of 4 July 2022 (edit) Sources: ANFP Official Web Site Manager: Juan José Luvera Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.