[3] The club plays a local derby known as the Clásico Regiomontano femenil against city rivals Tigres UANL.

[11] The second leg of this final at Estadio BBVA was at the time the highest attended club match in women's football history.

Unlike the previous final between these two clubs (Apertura 2019), Tigres was able to crown themselves champions after beating Monterrey on penalties (3–2) after a 1–1 draw on aggregate.

[16] With Eva Espejo as manager, the club was able to obtain its second league title by winning the Apertura 2021 tournament after defeating Tigres on penalties (1–3) after a 2–2 draw on aggregate.

[18] On the Clausura 2022, Monterrey ended the regular phase of the tournament 1st with 43 pts, but it was eliminated in the semi-finals of the playoffs by Pachuca.

[19][20] As the winner of the Apertura 2021 tournament, Monterrey qualified to play the 2022 Campeón de Campeones final against the Clausura 2022 champions C.D.

Monterrey reached the final of this tournament by beating Portland Thorns on penalties (3–2) after a 1–1 draw on regular time in the semi-finals.

[24] Colloquially known as "El Gigante de Acero" (Spanish for "The Steel Giant"),[25] the stadium is located in the adjacent city of Guadalupe, part of the Greater Monterrey area.