[2] The hospital provides comprehensive pediatric specialties and subspecialties to infants, children, teens, and young adults 0-21[3][4][5] throughout Michigan and the surrounding states.

Mott Children's Hospital also features a Level 1 Pediatric Trauma Center, 1 of 3 in the state.

The new facility for the C. S. Mott Children's and Von Voigtlander Women's Hospital, opened in December 2011[14][15] following the completion of a $754 million, five-year construction project.

[19][23] The Charles Stewart Mott foundation contributed $25 million to the construction of the new hospital.

[12] The building contains 348 single, private room beds divided between the children's and women's hospital including a dedicated pediatric emergency department and trauma center.

[24] The children's hospital is consistently ranked as one of the top pediatric centers in the country according to U.S. News & World Report.

Mott Children's Hospital successfully separated 1-year-old conjoined twins Sarabeth and Amelia Irwin.

[26][27][28] In November 2020, Dwayne "The Rock" Johnson collaborated with Microsoft and billionaire Bill Gates to donate Xbox Series X consoles to C.S.

In addition to the patient care units the hospital also has 16 operating rooms with 76 PACU beds.

Mott Children's Hospital has placed nationally in all 10 ranked pediatric specialties on U.S. News & World Report.

[41][42] As of the 2020-21 rankings, Von Voigtlander Women's Hospital has placed nationally as #39 in gynecology on the U.S. News & World Report.