[1] Among his most well-known achievements in the area of computer science was the introduction of Reverse Polish Notation[2][3] and the use in 1957 of a push-down pop-up stack.

For the DEUCE, he designed one of the first programming languages, later called GEORGE (General Order Generator),[8] which was based on Reverse Polish Notation.

Regardless of whether Hamblin independently invented the notation and its usage, he showed the merit, service, and advantage of the Reverse Polish way of writing programs for the processing on programmable computers and algorithms to make it happen.

Hamblin's work influenced the development of stack-based computers, their machine instructions, their arguments on a stack, and reference addresses.

In its very early period he corresponded with Arthur Prior between 1958 and 1965; this collaboration culminated with the so-called Hamblin implications.

Later in 1972 Hamblin independently rediscovered a form of duration calculus (interval logic), without being aware of the 1947 work of A. G. Walker on this topic, who was not interested in the tense aspect.

[9] Hamblin was familiar with ancient Greek and several Asian and Pacific languages and in 1984 published a polyglot phrasebook on 25 of the latter, including "Burmese, Korean, Japanese, Fijian and Tahitian".