It may be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins.

It probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin.

Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.

[5] The CacyBP/SIP complex instead, is known to be a part of stress respons, since it interacts with chaperone HSP90.

This article on a gene on human chromosome 1 is a stub.