The CBS Broadcast Center is a television and radio production facility located on the West Side of Midtown Manhattan in New York City.

The other two are the Ed Sullivan Theater, which hosts The Late Show with Stephen Colbert, along with the Times Square studios for CBS Mornings, located in the company's headquarters at One Astor Plaza.

The radio network, with offices at 1 East 53rd Street and studios at 49 East 52nd Street, near the old CBS corporate headquarters at 485 Madison Avenue, moved to the Broadcast Center in July 1964, while the television network's master control moved from Grand Central to the Broadcast Center in late 1964.

The company spent $14.5 million to create what was, at the time, "the largest 'self-contained' radio and television production center in the United States and the most modern broadcasting plant of its kind in the world," as the New York Tribune put it in 1961.

Until January 2000, the Broadcast Center was home to CBS-TV's soap opera As the World Turns, which moved to JC Studios in Brooklyn.

After a few months it was announced that Anderson Cooper's talk show would move into Studio 42 leaving its home in the Time Warner Center.

TBS news satire show Full Frontal with Samantha Bee recorded from the Broadcast Center from its 2016 premiere until the pandemic, before moving to home taping for several months.

On March 12, 2020, one day after COVID-19 was declared a pandemic, the CBS Broadcast Center was closed for disinfection after two employees tested positive for COVID-19.

[9][10][11] The Broadcast Center reopened on a limited basis on March 14, 2020, starting with the Saturday edition of CBS This Morning from Studio 57;[12] on March 18, ViacomCBS announced that its operations would again temporarily relocate from the Broadcast Center, with CBS This Morning moving to the set of The Late Show with Stephen Colbert at the Ed Sullivan Theater[13] and KCBS-TV again producing WCBS-TV's newscasts.

[6][18] At the time, the building covered 1,000,000 square feet (93,000 m2) and had large amounts of air rights, which permitted the development of skyscrapers on the site.