CCHCR1

It is also known as Coiled-Coil Alphahelical Rod Protein 1, C6orf18, Putative Gene 8 Protein, SBP, HCR (A-Helix Coiled-Coil Rod Homologue), pg8, StAR-Binding Protein, and Pg8.

Phylogenetic analysis with ClustalW indicated that CCHCR1 The CCHCR1 gene has The structure of CCHCR1 is primarily composed of alpha-helices, coils[clarification needed], and a small amount of beta sheets, according to PELE.

,[10] TOP3B,[11] Steroidogenic acute regulatory protein,[10] TRAF4,[12] HLA-C,[13] TCF19,[13] SNX29,[14] EEF1D,[15] and EEF1B2.

[15] In genetically engineered mice, certain CCHCR1 polymorphisms cause upregulation of the expression of cytokeratins 6 (KRT6A), 16 (KRT16) and 17 (KRT17) and change in expression in other genes associated with terminal differentiation and formation of the cornified cell envelope.

[16] Defective functioning of CCHCR1 may lead to abnormal keratinocyte proliferation which is a key feature of psoriasis.