Founded in 2006 as Club Deportivo Gerena, it plays in Tercera Federación – Group 10, holding home matches at San José.

Founded in 2006, Gerena first reached the Tercera División in 2013, after winning their Primera Andaluza group.

In 2015, the city's stadium was renamed to José Juan Romero Gil, the club's manager who took them to the fourth tier.

[1] In July 2023, amidst a financial crisis, Gerena was close to a name change to Internacional de Fútbol Sevilla Dos Hermanas,[2] but the move later fell through.

[3] In August of the following year, the move did materialize, with the club leaving the city of Gerena for Gines.