6303613706ENSG00000142615ENSMUSG00000058579P08217P05208NM_033440NM_007919NP_254275NP_031945Chymotrypsin-like elastase family member 2A is an enzyme that in humans is encoded by the CELA2A gene.

[5][6][7] Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin.

Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B.

In other species, elastase 2A has been shown to preferentially cleave proteins after leucine, methionine, and phenylalanine residues.

Clinical literature that describes human elastase 1 activity in the pancreas is actually referring to elastase 2A.