4X1V11698569710ENSG00000186635ENSMUSG00000032812Q96P48Q4LDD4NM_015242NM_001040118NM_001135190NM_001369489NM_001040111NM_001040112NM_027180NM_198096NP_001035207NP_001128662NP_056057NP_001356418NP_001394732Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 is a protein that in humans is encoded by the ARAP1 gene.

[5] The protein encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains.

In vitro, this protein displays RHO-GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3)-dependent ARF-GAP activity.

The RHO-GAP activity may mediate cell rounding and loss of stress fibers.

At least three transcript variants encoding different isoforms have been found for this gene, but the full-length natures of all variants have not been determined.