The centrally located city of Moncton was selected in 1940 for the site of a logistics supply base for military facilities in the Maritimes that were undergoing unprecedented expansion as a result of World War II.
Moncton Garrison was constructed in an industrial area on a railway spur line north of downtown, immediately east of the sprawling Canadian National Railways Moncton Shops facility.
Defence budget cuts in the 1990s following the end of the Cold War saw CFB Moncton identified for closure as a formation.
It stood down on April 1, 1996, and at that time was replaced by Canadian Forces Base Gagetown - Detachment Moncton, also known as Moncton Garrison, a unit of CFB Gagetown.
CFB Gagetown - Detachment Moncton supports the following units stationed at the garrison: In April 2012, the Department of National Defence announced that Moncton Garrison would be closed in the near future.