Aircraft flown at the base included the Avro Anson, Fairey Battle, Bristol Bolingbroke and Westland Lysander.

The aerodrome was listed with three runways as follows: [1] After the departure of the maintenance unit, most of the base was taken over by the army for use as the Royal Canadian School of Artillery (Anti-Aircraft) (RCSA(A.A.)).

The school provided training for anti-aircraft gunners, gunnery radar operators, technical assistants and artillery instructors.

However, reductions in the Canadian military meant that the base was no longer required and CFB Picton was closed in September 1969.

The Point Petre and South Bay Training Areas were located in the southeast corner of the county near Cherry Valley.

A transmitter site for the Military Aeronautical Communications System based at CFB Trenton is also located there.

The "Heights" as it was known locally, at its peak, was home to approximately 450 individuals with developmental disabilities and employed just as many staff, until deinstitutionalization became the norm and it closed in September 1999.

The base and Point Petre were also used to film Dieppe (1993), a TV movie by Canadian Broadcasting Corporation (CBC).