Minister of the Presidency José Luis Lupo Flores was an independent with links to the Revolutionary Left Movement (MIR) while Finance Minister Jacques Trigo Loubiere had been Superintendent of Banks for the Revolutionary Nationalist (MNR) government of Gonzalo Sánchez de Lozada.

Ministers Carlos Kempff Bruno, Walter Nuñez-Rodriguez, and Ramiro Cavero were new political figures though with noted inclinations towards Quiroga's Nationalsit Democratic Action (ADN) party.

The Quiroga cabinet was also significant in that many political "dinosaurs" were relieved of their positions in favor of younger ministers.

The appointment of Tomasa Yarhui as Minister Without Portfolio Responsible for Peasant Affairs and Indigenous Peoples as part of the second Quiroga cabinet was of particular note due to the fact that Yarhui was the first indigenous government minister in Bolivian history.

[9] Yarhui would by Quiroga's running mate in his second attempt to win a full term during the 2014 general elections.