Cadence Bank is a commercial bank with dual headquarters in Tupelo, Mississippi, and Houston, Texas, with operations in Alabama, Arkansas, Florida, Georgia, Louisiana, Mississippi, Missouri, Oklahoma, Tennessee, Texas, and Illinois.

In 1876, Raymond Trice and Company received a charter to create a bank in its hardware store in Verona, Mississippi.

[7] In October 2006, the bank acquired City Bancorp of Springfield, Missouri, for $170 million with half consisting of BancorpSouth stock and the remainder in cash.

[8] In January 2014, the bank acquired Ouachita Bancshares Corp. of Monroe, Louisiana, and Central Community Corporation of Temple, Texas.

Central Community Corporation was purchased for 7,250,000 shares of BancorpSouth's common stock plus $28.5 million in cash.

After nearly four years and multiple extension of completion dates, the bank received the necessary approvals in late 2017 to close the transactions.

[10] In April 2018, the bank acquired Icon Capital Corporation and its wholly owned subsidiary Icon Bank of Texas, National Association of Houston, Texas, for 4,125,000 shares of BancorpSouth's common stock plus $17.5 million in cash.

[23] In April 2003, the bank acquired WMS, LLC of Baton Rouge, Louisiana, which operated under the name of Wright & Percy Insurance.

Also, in July of the same year, the bank acquired Ramsey, Krug, Farrell and Lensing, Inc. of Little Rock, Arkansas.

[28] In April 2014, the bank acquired Knox Insurance Group, LLC of Lafayette, Louisiana.

[30] Cadence offers checking and savings accounts, loans, credit cards, wealth management, insurance, and financial advice.