In January 2023, General Motors (GM) announced their intention to enter the Cadillac brand into the Formula One World Championship in collaboration with Andretti Global.

[11] Andretti hired several alumni of Flavio Briatore's Renault / Team Enstone operation for senior roles, including Formula One CTO Pat Symonds,[6] technical director Nick Chester, aerodynamicist Jon Tomlinson, and advisor Naoki Tokunaga.

[15][16] Formula One Group CEO Stefano Domenicali stated that GM's commitment to the project was an "important and positive demonstration of the evolution of [the] sport".

[20] In December 2024, Ferrari announced that Cadillac had signed a multi-year deal to use their engines and gearboxes from 2026 onwards, until GM PPU develops an F1-ready power unit.

[18] GM PPU announced that it plans to spend $65-70 million building an engine factory for 300-350 employees, which is expected to open in the first quarter of 2027.