The holotype, found in Guyana, in the scrub of Iwokrama Forest, was 11.2 centimetres (4.4 in) in length, with 102 annuli.

Its colour in life was not recorded, but in preservative it was light yellow-brown with mottling.

Unlike previously reported, this species does have open external nares, and possesses a single, well-developed lung, and it is similar to other Microcaecilia in having an orbit mostly covered by bone (closed).

[4] Microcaecilia iwokramae is known from mixed low-stature scrub forest at 1,000 m (3,300 ft) above sea level.

Specimens could be found by digging soil, particularly under rotting wood or leaf litter or between the buttress roots of trees.