Cain City is a ghost town founded in 1915, 4 miles (6.4 km) southeast of Fredericksburg in Gillespie County, in the U.S. state of Texas.

It was established to be a station stop of the Fredericksburg and Northern Railway Company, of which the city's namesake Charlie Cain was a leading fundraiser.

[7] The initial board of directors consisted of James M. Dobie of Cotulla; C. B. Lucas of Berclair; Richard R. Russell, Thomas E. Mathis, W. W. Collier, J. H. Haile, and J. L. Browne, of San Antonio.

"[13] In 1913, San Antonio banker J.C. Stinson bought 324 acres (1.31 km2; 0.51 sq mi) in Gillespie County, in anticipation of the construction of the Fredericksburg and Northern Railway.

[15] In July 1916, the Cain City State Bank was added as a member of the Texas Bankers Association, with Stinson as its president.

The Mountain Home Hotel, opened by Mrs. Fletcher Hamilton of Illinois, was bought by J.C. Stinson and eventually sold to Mrs. Will Bird.

Edgar Tatsch and Theodore Keller opened a dance hall in 1927, but by that time the town was already in an advanced state of decline.