[2][3] Cain International was co-founded by Jonathan Goldstein and Todd Boehly in 2014,[4] with minority backing from Guggenheim Partners.

[12] Cain Hoy entered a joint venture with Galliard Homes in 2015 to develop high rise apartments in Canary Wharf.

[13][14] In 2014, Cain Hoy Enterprises loaned $167 million to SBE Entertainment Group as part of the company's recapitalization.

[18] By 2016, the firm had invested over $1.4 billion in real estate development,[19] and had begun to expand into the United States and Europe.

[29] In April 2021, Cain International and OKO Group, a Miami-based real estate development firm, received a loan from Bank OZK to a construct the Missoni Baia tower in South Brickell, Miami.

[32] Cain International and OKO Group also entered a joint venture to build One River, a highrise apartment in Fort Lauderdale.

[37][38] Cain International raised €324 million for its first European real estate fund, with backing from Goldman Sachs and Security Benefit Life Insurance Company.

[40] The company provided a $117 million loan to Lendlease in November 2021 to finance the construction of The Reed, a development project in the Chicago Loop.

[44][45] In April 2022, Blackstone Inc provided Cain International with £420 million in financing to develop the portfolio acquired in 2021.

[58] In November 2023, Cain extended a $240 million loan to Related Companies and Alta Developers for the construction of Casa Bella Residences, an apartment tower by B&B Italia.

[1] It also provided $47.3 million in funding to real estate firms Sumaida, Khurana and Bizzi, & Bilgili for the construction of The Fifth Miami Beach, an office tower in the South of Fifth neighbourhood designed by architect Alberto Campo Baeza.