Born in São Paulo, Brazil, De Cenco started his Italian career at Emilia-Romagna club Boca San Lazzaro, in Italian Serie D, the fifth division (from 1978 to 2014; Serie C refound in 2014) and top division of amateur (non fully professional) football.
He scored 14 goals in 2009–10 Serie D.[1] The club folded after relegation back to Eccellenza at the end of season.
In August 2010 De Cenco was signed by Serie A club A.C. Cesena on a free transfer.
He was farmed to A.C. Bellaria – Igea Marina in a co-ownership deal for €500 each, along with Alessio Petti.
[3] Despite Cesena relegated back to Serie B, De Cenco did not include in the pre-season camp of the Romagna-based side.
[20] On 25 August 2021, after his contract with Feralpisalò expired, De Cenco joined to Mantova 1911.