The Caleb H. Marshall House is a historic residential property at 53 Summer Street in St. Johnsbury, Vermont.

The property consists of a main house, which has a front-facing 2+1⁄2-story block with Italianate styling and a long rear ell, and a seven-car garage at the back of the lot.

A Colonial Revival porch extends across the front and around to the left side, supported by round columns set on a shingled skirt.

Marshall's son Caleb, a brass finisher by trade, is credited with updating the house with its Italianate features in 1870.

In 1919 his daughter sold the house to Harriet Frost, who operated what appears to be the first sanatorium in the town; it was probably established to handle cases of the 1918 influenza epidemic, and is the period from when the rear ell and the front porch date.