It includes many neighborhoods west and southwest of Downtown Los Angeles.

Approximately 40% of the district's residents are Hispanic, while African Americans and whites make up nearly a quarter each.

As of the 2020 redistricting, California's 37th congressional district is located in the South Los Angeles region.

The 37th district take in the city of Culver City, the Los Angeles neighborhoods of Jefferson Park, Hyde Park, Ladera, South Robertson, Crestview, Mid-City, Downtown Los Angeles, West Adams, South Los Angeles, Crenshaw, Leimert Park, Baldwin Hills, part of Carthay, part of Arlington Heights, and the north side of Century City, and the census-designated places Ladera Heights and View Park-Windsor Hills.

Due to redistricting after the 2010 United States census, the district has moved northwest within Los Angeles County and includes Culver City and Inglewood.