The district currently includes the South Bay region of San Diego County.

It encompasses the South Bay region of San Diego County.

It also encompasses the San Diego neighborhoods of Paradise Hills, Logan Heights, Encanto, Mountain View, Barrio Logan, Shelltown, Lincoln Park, Nestor, Otay Mesa, and South San Diego.

1992 • 1994 • 1996 • 1998 • 2000 • 2002 • 2004 • 2006 • 2008 • 2010 • 2012 • 2014 • 2016 • 2018 • 2020 • 2022 From 2003 through 2013, the district consisted of many of San Diego's northern and eastern suburbs, including Lakeside, Poway, Ramona, La Mesa, and Spring Valley.

Due to redistricting after the 2010 United States census, much of this area is now in the 50th district.