It begins as an east–west arterial road running from Lincoln to Newcastle, just west of Auburn.

Then after concurrencies with Interstate 80 and State Route 49 through Auburn, SR 193 resumes heading eastward from Cool to Georgetown, then turning south to rejoin SR 49 just north of Placerville.

The city has since been annexing more territory to include increasing areas of residential development, and thus SR 193's western end has been adjusted accordingly.

[7] Except where prefixed with a letter, postmiles were measured on the road as it was in 1964, based on the alignment that existed at the time, and do not necessarily reflect current mileage.

[8] Segments that remain unconstructed or have been relinquished to local control may be omitted.