[3] When they were children, Visitante would visit his brother at the Calle 13 (13th Street) of the El Conquistador subsection of Trujillo Alto, Puerto Rico, every week.

[3] While their first album was being mixed, Filiberto Ojeda Ríos, leader of the Puerto Rican revolutionary group known as Los Macheteros, was killed in the course of arrest by the FBI.

Angered by the FBI's action, Residente wrote a song protesting against what had happened to Ojeda and asked his record label to allow the group to release it on the Internet through viral marketing through Indymedia Puerto Rico, an alternative news website.

In 2006 the duo kept on working as they broke into a wider-music scene with at least two more smash hits that were played throughout Puerto Rico and U.S. Urban music radio and television stations, including the songs "Japón" ("Japan"), and "Suave" ("Soft/Slow").

They also toured Central and South America, playing "Atrévete-te-te" before an escola de samba in Venezuelan television, and also visiting, among others, Guatemala, Chile, Honduras and Colombia.

An example of this is the constant references made to the band and to Residente by satirical writer Fiquito Yunqué in the weekly pro-independence newspaper Claridad.

Some political adversaries of Acevedo dismissed this as a trick to ingratiate himself with Puerto Rican youth and pro-independence advocates, and was criticized by the local press due to the fact that an artist who seemingly promoted violence with their "Querido FBI" song was now supposed to be a role model for anti-violence.

They later filmed a video along with Voltio for "Chulín Culín Chunfly", where Residente, dressed as a priest and later as Bruce Lee, is given a severe beating by a gang.

[17] After recording a song titled "Tributo a la Policía", Calle 13 distributed the single free on the streets in front of the Police Headquarters of San Juan.

On November 8, 2007, Calle 13, along with Orishas, performed the song "Pa'l Norte" at the 8th Annual Latin Grammy Awards, held at the Mandalay Bay Events Center in Las Vegas, Nevada.

On 2008, their "Atrévete-te-te" song was a featured track on the game Grand Theft Auto IV, playing in the lineup of the fictional San Juan Sounds radio station.

On August 11, 2009, the duo was invited to Ecuador by Rafael Correa's government, serving as guests in the local celebrations that commemorate the coup that began the Ecuadorian War of Independence.

[27] On March 23, 2010, the band performed their first concert in Cuba, the event was held at the José Martí Anti-Imperialist Plaza before an estimated crowd that ranged between 500,000 and 900,000 fans.

During this event, Calle 13 received the international Cubadisco award from representatives of the Instituto Cubano de la Música (lit.

"[33] He also stated that the album continues to experiment with different styles of music, with collaborations with Omar Rodríguez-López from The Mars Volta on "Calma Pueblo", giving the song a "Beastie Boys vibe".

[33] The promotional tour for Entren Los Que Quieran featured over a hundred presentations in 2011, spanning most of Latin America and parts of Europe.

Among the most notable being serving as the sole representation of Puerto Rico at the inauguration of the Community of Latin American and Caribbean States and their performance at the 2011 Viña del Mar Festival, where Calle 13 decided to go against the event's rules, refusing further awards beyond a "Silver Torch" in order to avoid further interruption, despite being the most clamored artist in that night.

[34] On November 19, 2011, the group offered a concert in El Salvador where the entrance gate was fully paid in rice and beans, the collected food was subsequently donated to flood victims in that country.

[35] Pérez also remixed an exclusive version of "El Hormiguero" for four-time world boxing champion Miguel Cotto, who used it in his entrance prior to a successful title defense on December 3, 2011.

Upon release, the music video for "Calma Pueblo" generated controversy for its violence and full-frontal nudity, which the band claims is a metaphor for self-liberation.

In the press conference that followed, the group was interviewed by journalist Elvis Castillo of VENFM regarding his support to some elements of the Latin American left-wing.

In the event, Pérez was heralded as the "Roberto Clemente of modern music" by host Luis Gutierrez, only to respond that he was "merely another member of [the Puerto Rican people] who decided to express [his] message".

[38] On November 13, 2013, the group released the track and video "Multi Viral", which featured WikiLeaks founder Julian Assange and Palestinian singer Kamilya Jubran on vocals and Tom Morello on guitar.

[39][40][41] In December 2013, they announced that their new album would be named Multi Viral and it would be followed by a Latin American tour, which saw the band performing in Paraguay, Uruguay, Chile, Venezuela, Colombia, Costa Rica and Mexico.

[42] The tour unofficially began at the University of Puerto Rico, Río Piedras Campus in San Juan, where Calle 13 held an impromptu free concert on February 25, 2014.

[43] The concert, which featured interludes where the group opposed a revision in the UPR's enrollment fee and allowed a low income child to voice the concerns of his community, managed to attract an estimate of 50,000 fans.

[46] Despite recognizing that his political ideology conflicted with the inmovilist conservative ideals of governor Alejandro García Padilla, Pérez accompanied the same child to a reunion in La Fortaleza the following day.

In their recent tours around Latin America they have added different musical elements according to the place the band is playing in, yet many of their songs carry the traditional reggaeton "Dem Bow" beat such as in their hit "Tango del Pecado" and the remix to "Suave".

He has also said that he is influenced by music from Central Europe such as Fanfare Ciocarlia (particularly its collaboration with Romani band Kaloome, also known as The Gypsy Kings and Queens) and Emir Kusturica's group, The No Smoking Orchestra.

[57] In live presentations, Visitante can be seen playing a variety of instruments: an electric guitar, synthesizers, an accordion, a melodica, a Puerto Rican cuatro and a theremin.