The simple-station Calle 45 - American School Way is part of the TransMilenio mass-transit system of Bogotá, Colombia, opened in year 2000.

The station is located north of downtown Bogotá, specifically on Avenida Caracas, between Calles 42 and 45.

In 2000, phase one of the TransMilenio system was opened between Portal de la 80 and Tercer Milenio, including this station.

It also serves the neighborhoods of Palermo, Sucre, Santa Teresita, and Clinica Nueva.

On March 9, 2012, protests lodged by mostly young children in groups of up to 200, blocked in several times and up to 3 hours in the trunk stations Caracas.