It is noted as location for luxury flagship stores.

[2] Initially known as Bulevar Narváez (Narváez Boulevard),[3] the street received its current name following the 1868 Glorious Revolution, during which the namesake, the General Serrano (who had lived in the street), took a leading role.

[2][3] In the 2010s the street became one the favourite grounds for real estate operations of Venezuelan fortunes.

[4] The street starts at the Puerta de Alcalá.

[5] Going north across the well-off Salamanca District, historically linked to the upper class and to the presence of luxury stores,[6] Serrano ends at the Plaza de la República del Ecuador,[7] in the junction with the calle del Príncipe de Vergara, in the Chamartín District.