Caloocan's 2nd congressional district, also known as South Caloocan district, is one of the three congressional districts of the Philippines in the city of Caloocan.

It has been represented in the House of Representatives of the Philippines since 1987.

[3] The district consists of the entire South Caloocan barangays south of Circumferential Road 4 (including EDSA): Barangays 5 to 76 in Zones 1 to 7 and Barangays 86 to 131 in Zones 8 to 11.

[4][5] It is currently represented in the 19th Congress by Mary Mitzi Cajayon-Uy of Lakas–CMD.

[6][7]