Calusco d'Adda (Bergamasque, Brianzöö: Calösch) is a comune (municipality) in the Province of Bergamo in the Italian region of Lombardy, located about 35 kilometres (22 mi) northeast of Milan and about 14 kilometres (9 mi) west of Bergamo.

Calusco d'Adda borders the following municipalities: Carvico, Medolago, Paderno d'Adda, Robbiate, Solza, Terno d'Isola, Villa d'Adda.

Calusco d'Adda is twinned with:

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