The hospital specialises in surgery, critical care, oncology, and a broad range of other medical services, and is one of Tasmania's most prominent private healthcare institutions.

In 2024, Calvary's emergency department resumed full-time services after staffing shortages in the public healthcare sector led to reduced hours.

Calvary Hospital is affiliated with the Catholic Church and operates under the auspices of the Little Company of Mary Health Care.

It is closely linked to Tasmania’s private healthcare network and collaborates with a range of local and national medical organisations.

The patient, who suffered complications after the surgery, stated that she had received conflicting information from different staff members and had to wait for several weeks for a response.